Both may be debased to be sure, but they may be exemplary.
To _affect_ means to feign or to have an influence upon, to
_effect_ to bring to pass. Thus "He affects a fondness for classical
music," "The little orphan's story affected those who heard it"; "We
effected a compromise." _Affect_ is never properly used as a noun.
_Effect_ as a noun means result, consequence, or practical operation.
Thus "The shot took instant effect"; "He put this idea into effect."
A disease is _contagious_ when the only way to catch it is through
direct contact with a person already having it, or through contact with
articles such a person has used. A disease is _infectious_ when it is
presumably caused, not by contact with a person, but through widespread
general conditions, as of climate or sanitation.
Our _knowledge_ is our acquaintance with a fact, or the sum total of
our information. Our _wisdom_ is our intellectual and spiritual
discernment, to which our knowledge is one of the contributors.
_Knowledge_ comprises the materials; _wisdom_ the ability to use
them to practical advantage and to worthy or noble purpose.
_Knowledge_ is mental possession; _wisdom_ is mental and moral
power.
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